NMT1 antibody (AA 1-496)

Catalog No. ABIN5776038

This Mouse Monoclonal antibody specifically detects NMT1 in ELISA, WB, IF and ICC. It exhibits reactivity toward Human.

Quick Overview for NMT1 antibody (AA 1-496) (ABIN5776038)

Target: NMT1 (N-Myristoyltransferase 1 (NMT1))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This NMT1 antibody is un-conjugated

Application: ELISA, Western Blotting (WB), Immunofluorescence (IF), Immunocytochemistry (ICC)

Clone: AT2C8

Product Details anti-NMT1 Antibody

Binding Specificity: AA 1-496

Purpose: Human NMT1 antibody

Purification: Purified

Immunogen: Recombinant human NMT1 (1-496aa) purified from E. coli

Isotype: IgG2a kappa

Application Details

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Phosphate-Buffered Saline ( pH 7.4) with 0.02 % Sodium Azide, 10 % glycerol

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C,-80 °C

Storage Comment: Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

Target Details for NMT1

Target: NMT1 (N-Myristoyltransferase 1 (NMT1))

Alternative Name: NMT1

Background: Myristate, a rare 14-carbon saturated fatty acid, is cotranslationally attached by an amide linkage to the N-terminal glycine residue of cellular and viral proteins with diverse functions. N-myristoyltransferase catalyzes the transfer of myristate from CoA to proteins. N-myristoylation appears to be irreversible and is required for full expression of the biologic activities of several N-myristoylated proteins, including the alpha subunit of the signal-transducing guanine nucleotide-binding protein (G protein) GO. Recombinant human NMT1 protein, fused to His-tag at N-terminus, was expressed in E. coli and purified by using conventional chromatography techniques.

NCBI Accession: NP_066565

Pathways: Regulation of G-Protein Coupled Receptor Protein Signaling